Key result
Therapeutic drug monitoring increases the safety of Class I antiarrhythmic agents, digoxin, and perhexiline, and is useful for monitoring amiodarone compliance and toxicity.
Why the study?
Does therapeutic drug monitoring improve the safety and administration of antiarrhythmic drugs?
Design
Review
Authors
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Supports TDM for Class I agents, digoxin, and perhexiline; leaves open prospective validation of targets and outcomes.
Does therapeutic drug monitoring improve the safety and administration of antiarrhythmic drugs?
Therapeutic drug monitoring is valuable for enhancing the safety of specific antiarrhythmic agents, particularly Class I drugs, amiodarone, digoxin, and perhexiline.
Campbell et al. (2001) conducted a review in Antiarrhythmic drug therapy. Therapeutic drug monitoring was evaluated. Therapeutic drug monitoring increases the safety of Class I antiarrhythmic agents, digoxin, and perhexiline, and is useful for monitoring amiodarone compliance and toxicity.
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