What is the clinical evidence from this study?

Study design: Observational. Population: Idiopathic scoliosis (n=1241). Intervention: Surgical correction of idiopathic scoliosis. Primary outcome: Intraoperative blood loss volume.

What question did this study set out to answer?

To quantitatively assess the volume and severity of intraoperative blood loss across different operative stages and surgical techniques during the correction of idiopathic scoliosis.

June 6, 2012Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika)Open Access

Retrospective Analysis of Intraoperative Blood Loss During Surgery for Idiopathic Scoliosis

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Key result

Intraoperative blood loss during surgical correction of idiopathic scoliosis averaged 20.0 to 40.0% of circulatory blood volume, with multilevel vertebrectomy causing the highest loss (1242.9 ml).

Why the study?

What is the volume of intraoperative blood loss during different stages and methods of surgical correction for idiopathic scoliosis?

Key Points

To quantitatively assess the volume and severity of intraoperative blood loss across different operative stages and surgical techniques during the correction of idiopathic scoliosis.
Retrospective analysis of intraoperative blood loss across surgical stages in N=1,241 operated patients with idiopathic scoliosis.
Procedures comprised multi-stage interventions (n=581; 46.8%), posterior fusion (n=660; 53.2%), and multilevel corrective vertebrectomy (n=72; 12.4%).
Anesthesia regimens included total intravenous anesthesia (propofol, fentanyl, tracrium) or inhaled sevoflurane with fentanyl and tracrium.
Total intraoperative blood loss during multi-stage surgery was 967.4 ± 43.6 ml with segmental hook instrumentation versus 1135.9 ± 139.5 ml with hybrid instrumentation.
Posterior-only fusion incurred 865.5 ± 40.1 ml of blood loss with segmental hooks compared to 1049.9 ± 75.5 ml with hybrid instrumentation, whereas multilevel vertebrectomy yielded the highest blood loss at 1242.9 ± 121.8 ml.
Intraoperative blood loss averaged between 20.0% and 40.0% of total circulating blood volume, with surgical duration confirmed as the primary factor influencing blood loss volume.

Study Design

Type

Observational (n=1,241)

Structured PICO

What is the volume of intraoperative blood loss during different stages and methods of surgical correction for idiopathic scoliosis?

Population

1,241 patients undergoing surgical correction of idiopathic scoliosis.

Exposure

Surgical correction of idiopathic scoliosis (multi-stage, posterior fusion, multilevel corrective vertebrectomy)

Outcome

Intraoperative blood loss volume and severity during stages of surgical correctionsafety

Intraoperative blood loss during surgical correction of idiopathic scoliosis is substantial, averaging 20-40% of circulatory blood volume, and is primarily influenced by surgery duration.

Discussion

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Implication

Anticipate substantial blood loss in idiopathic scoliosis surgery, especially with vertebrectomy; Level 3 data leaves open prospective mitigation trials.

Cite This Study

Mn et al. (2012) conducted an observational in Idiopathic scoliosis (n=1,241). Surgical correction of idiopathic scoliosis was evaluated on Intraoperative blood loss volume. Intraoperative blood loss during surgical correction of idiopathic scoliosis averaged 20.0 to 40.0% of circulatory blood volume, with multilevel vertebrectomy causing the highest loss (1242.9 ml).

synapsesocial.com/papers/6aa00f5e7d1060b777b56ebe https://doi.org/10.14531/ss2012.2.70-78

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Implication

Anticipate substantial blood loss in idiopathic scoliosis surgery, especially with vertebrectomy; Level 3 data leaves open prospective mitigation trials.

Retrospective Analysis of Intraoperative Blood Loss During Surgery for Idiopathic Scoliosis

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

Retrospective Analysis of Intraoperative Blood Loss During Surgery for Idiopathic Scoliosis

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider