Key result
Synchronous activation of bulbo-spinal inspiratory neurones via intraspinal stimulation had little or no effect on the duration of inspiration or expiration in cats.
Population
Chloralose-urethane anaesthetized, paralysed, vagotomized and artificially ventilated cats
Design
Preclinical
Authors
Loading...
Does not implicate bulbo-spinal inspiratory neurones in respiratory timing; hypothesis-generating for their role, requires confirmation in other models.
Synchronous activation of bulbo-spinal inspiratory neurones does not significantly alter respiratory timing, suggesting they are not responsible for generating respiratory timing signals.
Feldman et al. (1984) studied this question. Intraspinal stimulation was evaluated on Phrenic nerve discharge and respiratory timing. Synchronous activation of bulbo-spinal inspiratory neurones via intraspinal stimulation had little or no effect on the duration of inspiration or expiration in cats.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: