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A number of rac. and optically active homoberbines have been synthesized from substituted 1‐phenethyltetrahydroisoquinolines and formaldehyde by an acid catalyzed cyclization. These homoberbines represent a new class of heterocyclic compounds which are isomeric with the homoaporphine alkaloids.
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BROSSI et al. (1969) studied this question.
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