Key result
Surgical and natural menopause were associated with significantly higher carotid femoral and brachial ankle pulse wave velocities compared to premenopausal status, indicating increased arterial stiffness.
Why the study?
Is natural or surgical menopause associated with increased arterial stiffness compared to premenopausal status?
Cross-Sectional (n=127)
Is natural or surgical menopause associated with increased arterial stiffness compared to premenopausal status?
Absolute Event Rate: 1104.4% vs 867.04%
p-value: p=<0.005
Both natural and surgical menopause are associated with increased arterial stiffness compared to premenopausal status, suggesting a mechanism for increased cardiovascular risk.
Menopause was associated with increased arterial stiffness; leaves open causal links and need for longitudinal CVD outcome studies.
BACKGROUND: Menopause is associated with increased cardiovascular disease (CVD) risk. Arterial stiffness, a biomarker of vascular aging, increases the risk for CVD. AIMS AND OBJECTIVES: The study was aimed to determine whether menopause is associated with arterial stiffness amongst natural and surgical menopausal women. MATERIALS AND METHODS: We conducted a cross-sectional study amongst natural postmenopausal women, with Surgical menopause and Premenopausal. Arterial stiffness was measured by Periscopy TM. Large artery stiffness may be an important mechanism by which hysterectomy increases the risk of cardiovascular disease in postmenopausal women. RESULTS: Carotid femoral pulse wave velocity (cfPWV) and Brachial Ankle Pulse wave velocity (baPWV) were significantly higher in surgical and natural menopause compared to women with Premenopausal group.
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Pandey et al. (2018) conducted a cross-sectional in Menopause (n=127). Natural and surgical menopause vs. Premenopausal status was evaluated on Carotid femoral pulse wave velocity (cfPWV) (p=<0.005). Surgical and natural menopause were associated with significantly higher carotid femoral and brachial ankle pulse wave velocities compared to premenopausal status, indicating increased arterial stiffness.
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