Key result
Maintaining a regular high physical activity level over 25 years was associated with significantly lower mean coronary artery calcification compared to low-to-moderate activity (10.7 vs 286.1, p<0.001) in middle-aged men.
Why the study?
Does maintaining high or very high physical activity reduce subclinical atherosclerosis compared to low-to-moderate physical activity in asymptomatic middle-aged men?
Population
101 asymptomatic white men, free of cardiovascular symptoms and chronic diseases, not taking any CVD…
Comparison
High or very high exercise-related energy… vs Low-to-moderate physical activity maintained…
Design
Cohort, A single operator blinded to other analyzed variables of the…
Follow-up
mean 24.7 ± 4.1 years
Authors
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Sustained high physical activity may protect against subclinical atherosclerosis in middle-aged men; leaves open whether benefits extend to clinical events or other groups.
Cohort (n=101)
No
Does maintaining high or very high physical activity reduce subclinical atherosclerosis compared to low-to-moderate physical activity in asymptomatic middle-aged men?
Absolute Event Rate: 10.7% vs 286.1%
p-value: p=<0.001
Kwaśniewska et al. (2014) conducted a cohort in Subclinical atherosclerosis (n=101). High physical activity (2050-3840 kcal/week) vs. Low-to-moderate physical activity (<2050 kcal/week) was evaluated on Mean coronary artery calcification (CAC) score (p=<0.001). Maintaining a regular high physical activity level over 25 years was associated with significantly lower mean coronary artery calcification compared to low-to-moderate activity (10.7 vs 286.1, p<0.001) in middle-aged men.
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