Enhanced fluorescence emission is detected from interacting protein pairs of dichlorotriazinylaminofluorescein-streptavidin and biotinylated bovine serum albumin (see figure) that are adsorbed onto periodically spaced, square-patterned ZnO nanostructures. This florescence-enhancement capability of nanoscale ZnO and its potential easy integration into biosensor arrays may allow ultrasensitive protein detection, which is needed in the areas of biomedical research and in large-scale testing and screening.
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Dorfman et al. (2006) studied this question.
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