Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1TGF-β1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells2005 · 987 citations
2. 2Directed evolution of green fluorescent protein by a new versatile PCR strategy for site-directed and semi-random mutagenesis2000 · 355 citations
3. 3Smad2 and Smad3 Are Redundantly Essential for the TGF-β–Mediated Regulation of Regulatory T Plasticity and Th1 Development2010 · 339 citations
4. 4Notch1 and TGFβ1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells2008 · 189 citations
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