Key result
Molecular characterization of 21 ASFV-positive samples from pigs in Tanzania revealed that symptomatic cases belonged to genotype II, whereas asymptomatic cases belonged to genotype IX.
Why the study?
In African swine fever endemic countries, reports of circulating strains with differing virulence and clinical symptoms are increasing, following recorded outbreaks of symptomatic and asymptomatic cases in Tanzania.
Population
35 clinical samples from four African swine fever outbreaks in Tanzania
Comparison
Samples from symptomatic pigs vs asymptomatic pigs
Design
Molecular epidemiological and phylogenetic study
Authors
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May signal variable-virulence ASFV circulation in Tanzania; leaves open needs for genomic surveillance and prospective control studies.
Observational (n=35)
The study demonstrates the simultaneous circulation of two different ASFV genotypes (II and IX) with varying pathogenicity in Tanzania, highlighting the role of sub-clinically infected pigs in viral persistence.
Chang’a et al. (2019) conducted an observational in African swine fever (n=35). Symptomatic vs asymptomatic infection was evaluated on ASFV detection and genotype characterization. Molecular characterization of 21 ASFV-positive samples from pigs in Tanzania revealed that symptomatic cases belonged to genotype II, whereas asymptomatic cases belonged to genotype IX.
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