Answers are grounded in this paper and cite their sources.
The reaction of o‐phthaldehyde with potassium cyanide and methylamine hydrochloride afforded 1‐cyano‐2‐methylisoindole (1) in 92% yield. Possible mechanism and supporting nmr, ir, mass spectrum and single X‐ray structure analysis for 1 are discussed. The X‐ray study revealed that the true structure of 1 can best be represented as a resonance hybrid of the canonical forms a, b, c and d.
No takes yet. Share an insight, caveat, or question.
D'Amico et al. (1983) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: