Key result
Intracoronary streptokinase infusion for acute myocardial infarction was associated with reduced in-hospital mortality (4.4%) compared to conventional medical therapy (18.6%).
Why the study?
Does intracoronary streptokinase infusion reduce in-hospital mortality in patients with acute myocardial infarction compared to conventional medical therapy?
Population
628 consecutive patients admitted with acute myocardial infarction. The intervention group excluded patients…
Comparison
Intracoronary streptokinase infusion to the… vs Conventional medical therapy during…
Design
Cohort
Follow-up
In-hospital
Authors
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Supports hypothesis of benefit in AMI; leaves open confirmation in randomized trials.
Cohort (n=628)
No
Does intracoronary streptokinase infusion reduce in-hospital mortality in patients with acute myocardial infarction compared to conventional medical therapy?
Absolute Event Rate: 4.4% vs 18.6%
Intracoronary streptokinase treatment in acute myocardial infarction is associated with significantly reduced in-hospital mortality compared to conventional medical therapy.
Salem et al. (1987) conducted a cohort in acute myocardial infarction (n=628). Intracoronary streptokinase (IC-SK) vs. Conventional medical therapy was evaluated on In-hospital mortality. Intracoronary streptokinase infusion for acute myocardial infarction was associated with reduced in-hospital mortality (4.4%) compared to conventional medical therapy (18.6%).
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