The trace element content of various intravenous solutions was investigated, using atomic absorption and neutron activation analysis methods. The variable content of zinc, calcium, and magnesium led us to seek a source of contamination. Quantities of zinc ranging from 10.75 mug to 132 mug were leached from the rubber stoppers when placed in 0.1N nitric acid for a period of 96 hours. Calcium and magnesium were also leached from the stoppers, but in lesser amounts.
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Mary M. Jetton (1976) studied this question.
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