Key result
Minimally invasive esophagectomy was associated with a trend toward better 1-year survival compared to open esophagectomy (OR 0.68; 95% CI 0.46-1.01; P=0.058).
Why the study?
Does minimally invasive esophagectomy improve survival and clinical outcomes compared to open esophagectomy in patients with esophageal cancer?
Cohort (n=18,673)
Yes
Does minimally invasive esophagectomy improve survival and clinical outcomes compared to open esophagectomy in patients with esophageal cancer?
Odds Ratio: 0.68 (95% CI 0.46–1.01)
p-value: p=0.058
Minimally invasive esophagectomy has seen exponential uptake in England and appears to offer similar short-term outcomes to open surgery, with a potential trend toward improved 1-year survival.
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Does not support practice change; leaves open whether minimally invasive esophagectomy improves survival in esophageal cancer.
Lazzarino et al. (2010) conducted a cohort in esophageal cancer (n=18,673). Minimally invasive esophagectomy vs. Open esophagectomy was evaluated on 1-year survival (OR 0.68, 95% CI 0.46-1.01, p=0.058). Minimally invasive esophagectomy was associated with a trend toward better 1-year survival compared to open esophagectomy (OR 0.68; 95% CI 0.46-1.01; P=0.058).
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