Key result
Additional linear ablation from the superior vena cava to the right atrial septum after CPVI significantly reduced atrial fibrillation recurrence compared to CPVI alone (6% vs 27%, P<0.001).
Why the study?
Does additional linear ablation from the superior vena cava to the right atrial septum after pulmonary vein isolation reduce recurrence in patients with paroxysmal atrial fibrillation?
Population
200 patients with paroxysmal atrial fibrillation (PAF), mean age 56.8 ± 11.7 years, 74.5% male.
Comparison
Circumferential pulmonary vein isolation plus… vs Circumferential pulmonary vein isolation alone…
Design
RCT, randomly assigned
Follow-up
12.2 ± 5.3 months
Authors
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Adding SVC-RA line to CPVI was associated with lower PAF recurrence; leaves open need for confirmatory trials before practice change.
RCT (n=200)
randomly assigned
Does additional linear ablation from the superior vena cava to the right atrial septum after pulmonary vein isolation reduce recurrence in patients with paroxysmal atrial fibrillation?
Absolute Event Rate: 6% vs 27%
p-value: p=<0.001
Additional linear ablation from the superior vena cava to the right atrial septum after pulmonary vein isolation significantly reduces the recurrence of paroxysmal atrial fibrillation, despite a longer procedure time.
Kang et al. (2014) conducted an RCT in paroxysmal atrial fibrillation (n=200). Circumferential pulmonary vein isolation (CPVI) + additional linear ablation from superior vena cava to right atrial septum (SVC-L) vs. CPVI alone was evaluated on Recurrence rate (p=<0.001). Additional linear ablation from the superior vena cava to the right atrial septum after CPVI significantly reduced atrial fibrillation recurrence compared to CPVI alone (6% vs 27%, P<0.001).
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