A Review: On Human Short Stature

Human height is a polygenic and complex character control by numerous genes, due to these many problems are related to it one of them is short stature, in which individuals do not achieve standard height compare to others.What are the genes and other factors involved in it, to know it we go thought resent and old published available data present and research articles, review articles, short and long communication and other data related to it.By going through research and literature we came to know that Short stature may be due genes or Short Stature homeobox (SHOX) region present on the pseudo autosomal region (PAR1) of both X and Y chromosome contains and major genes for human growth defect in it ultimately results in short stature or defect in protein which have effect on height and results of protein are on hormones which is also major contributor of Short stature and also that Growth hormones and insulin like growth factors are very important for achievement of normal height and defect in any one can leads to short stature.To get rid of Short stature researchers developed Recombinant human growth hormones therapy and recombinant insulin-like growth factor to treat short stature.we conclude that genes responsible for short stature are present in SHOX region, proteins are involved as well as hormones, we can treat the short stature with the help of Recombinant Human growth hormones and insulin like growth factors.