All articles of this category The synthesis of improved optically active selenium compounds for electrophilic additions to C=C double bonds is described. These reagents allow the formation of methoxyselenenylated products with high diastereoselectivities (up to 93% de). Intramolecular aminoselenenylations with chiral selenium electrophiles provide a short route to tetrahydroisoquinoline alkaloids. asymmetric synthesis - chiral diselenides - chirality - isoquinoline alkaloids - selenium
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Wirth et al. (1998) studied this question.