Chiral Preparation of (R)- and (S)-3-(Benzyloxy)-4,4-dimethyl-1-pentene

All articles of this category Facile routes for the preparation of an optically active allylic ether bearing the tert -butyl group at an allylic chiral center, i.e. 2-(benzyloxy)-3,3-dimethyl-1-pentene, in both ( R )- and ( S )-enantiomeric forms, which are expected to be promising, efficient dipolarophiles in highly stereoselective asymmetric nitrone cycloaddition, have been developed, utilizing commercially available L- tert -leucine and ( R )-pantolactone, respectively, as chiral precursors.