Key result
Microarray expression profiling of cardiovascular tissues and cells has identified unique subsets of genes associated with coronary artery disease, myocardial infarction, and heart failure.
Design
Review
Authors
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These associations require validation; leaves open translation to clinical biomarkers or therapies.
Microarray technology enables high-throughput global transcriptomic profiling to identify novel genes and pathways involved in cardiovascular diseases, complementing positional cloning and proteomics.
Archacki et al. (2004) conducted a review in Cardiovascular disease. Microarray analysis was evaluated. Microarray expression profiling of cardiovascular tissues and cells has identified unique subsets of genes associated with coronary artery disease, myocardial infarction, and heart failure.