Key result
ABCB1 gene C3435T polymorphisms and specific haplotypes (C-T-T, T-G-C, T-T-T) are associated with aspirin resistance in patients with ischemic stroke.
Why the study?
Are ABCB1 gene polymorphisms associated with aspirin resistance in patients with ischemic stroke?
Are ABCB1 gene polymorphisms associated with aspirin resistance in patients with ischemic stroke?
ABCB1 gene polymorphisms (C3435T) and specific haplotypes are associated with aspirin resistance in patients with ischemic stroke.
Answers are grounded in this paper and cite their sources.
ABCB1 variants may influence aspirin response in stroke; hypothesis-generating and should not yet change practice.
The polymorphisms of C3435T in the ABCB1 gene have a relationship with AR in the patients with ischemic stroke. The haplotypes (C-T-T, T-G-C, T-T-T) are also related to the AR in the patients with ischemic stroke.
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Zy et al. (2016) studied this question. ABCB1 gene C3435T polymorphisms and specific haplotypes (C-T-T, T-G-C, T-T-T) are associated with aspirin resistance in patients with ischemic stroke.
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