Key result
A 27-year-old woman with a mitral valve prosthesis exhibited coumarin resistance, maintaining a normal prothrombin time despite receiving 15 to 20 mg/day of sodium warfarin.
Case Report (n=1)
This case report highlights a rare instance of apparent hereditary coumarin resistance in a Black patient requiring anticoagulation for a mechanical heart valve.
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May require alternative anticoagulants in apparent warfarin-resistant mechanical valves; leaves open hereditary mechanisms in diverse populations.
JAMES ZAGER (1973) conducted a case report in Coumarin resistance (n=1). Sodium warfarin was evaluated on Prothrombin time. A 27-year-old woman with a mitral valve prosthesis exhibited coumarin resistance, maintaining a normal prothrombin time despite receiving 15 to 20 mg/day of sodium warfarin.
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