Ligation of Patent Ductus Arteriosus in Preterm Infant with Comorbidities: An Unforgotten Nightmare

Patent ductus arteriosus (PDA) is a common congenital anomaly in preterm infants. We report here a case of 28-day-old preterm infant, weighing 1.6 kg, with significant PDA, having bronchopulmonary dysplasia, necrotizing enterocolitis, intraventricular hemorrhage, hydrocephalus, and meningitis; presented for PDA ligation in view of prolonged ventilator dependence, non-responsiveness to pharmacological therapy for PDA closure, and continuous worsening of hemodynamics due to the presence of large PDA.