Key result
Analysis of media from cultured rat cardiac stem cells and neonatal ventricular myocytes identified 83 unique proteins, with specific factors found to affect rat CSC proliferation.
Identification of the secretome of rat cardiac stem cells and neonatal cardiomyocytes reveals specific paracrine factors that influence stem cell proliferation, which may be relevant for cardiac cell therapy.
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Does not support clinical translation; leaves open paracrine factor roles in human cardiac regeneration.
Št́astná et al. (2009) studied this question. Cultured rat cardiac stem cells and neonatal rat ventricular myocytes vs. Media alone was evaluated on Identification of secreted proteins. Analysis of media from cultured rat cardiac stem cells and neonatal ventricular myocytes identified 83 unique proteins, with specific factors found to affect rat CSC proliferation.
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