Key result
Independent stimulation of atria and ventricles in dogs showed the frequency of A-V waves was linearly related to ventricular heart rate, with a predicted frequency of zero when rates are identical.
Why the study?
Does asynchronous contraction of atria and ventricles modulate periodic oscillations in haemodynamic parameters in open-chest anaesthetized dogs?
Population
open-chest anaesthetized dogs
Design
Preclinical
Authors
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AV asynchrony may drive haemodynamic oscillations in canine models; hypothesis-generating for clinical dyssynchrony effects.
Does asynchronous contraction of atria and ventricles modulate periodic oscillations in haemodynamic parameters in open-chest anaesthetized dogs?
Experimental atrioventricular dissociation in dogs demonstrates that asynchronous atrial and ventricular contraction produces distinct 'A-V' waves, causing irregular blood flow dependent on the degree of asynchrony.
Kedem et al. (1980) studied Atrioventricular dissociation. Independent stimulation of atria and ventricles was evaluated on Frequency of A-V waves. Independent stimulation of atria and ventricles in dogs showed the frequency of A-V waves was linearly related to ventricular heart rate, with a predicted frequency of zero when rates are identical.
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