Key result
Ventilation and perfusion lung imaging revealing multiple branching perfusion defects in a patient with advanced ovarian carcinoma was found to be caused by pulmonary thromboembolism on autopsy.
Case Report (n=1)
Pulmonary thromboembolism should be considered in the differential diagnosis for patients presenting with multiple branching perfusion defects on lung imaging.
Multiple branching perfusion defects warrant thromboembolism consideration in advanced ovarian cancer; single case leaves broader differential applicability open.
A 46-year-old woman with advanced ovarian carcinoma had progressive dyspnea and was evaluated with ventilation and perfusion lung imaging. A characteristic pattern of multiple branching perfusion defects of a segmental nature on the perfusion scan suggested tumor microembolism and lymphangitic carcinomatosis. However, in this case, this pattern was associated with pulmonary thromboembolism and was documented by the post mortem examination. Pulmonary thromboembolism should be included among the differential diagnoses in a patient with clinical symptoms and a perfusion scan that reveals multiple branching perfusion defects.
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SHADAN et al. (1999) conducted a case report in Advanced ovarian carcinoma with progressive dyspnea (n=1). Ventilation and perfusion lung imaging was evaluated on Diagnosis of pulmonary thromboembolism. Ventilation and perfusion lung imaging revealing multiple branching perfusion defects in a patient with advanced ovarian carcinoma was found to be caused by pulmonary thromboembolism on autopsy.
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