Key result
In 50 postnatal BVDV outbreaks in cattle, acute infections and mucosal disease occurred with similar frequency, with no significant differences in morbidity, mortality, or lesion distribution.
Why the study?
BVDV is an important pathogen causing considerable economic losses worldwide and remains endemic in Argentina, where there is no national control program.
Observational (n=50)
BVDV remains endemic in central Argentina with BVDV-1b as the predominant subtype, highlighting the need for targeted vaccination and elimination of persistently infected animals.
Bovine viral diarrhea virus (BVDV) is an important pathogen in cattle and causes considerable economic losses worldwide. In Argentina, where there is no national control program, BVDV remains endemic. In this retrospective study, the epidemiological, clinical and pathological features of postnatal BVDV-associated diseases in 50 outbreaks in central Argentina (1995-2024) were analyzed. Data were obtained from field reports, necropsies, and virological results (virus isolation, RT-nPCR, immunochromatography). No seasonal pattern was found. Acute infections (AIs) and mucosal disease (MD) occurred with similar frequency. Clinical signs included salivation, weakness, emaciation and diarrhea. The lesions were widespread and involved the gastrointestinal tract, skin, lymphoid tissues and spleen. Although MD cases has more extensive tissue involvement, no significant differences in morbidity, mortality or distribution of lesions were observed between AIs and MD. BVDV-1b was the most frequently detected subtype. These results highlight the challenges of BVDV control in extensive production systems. Strengthening diagnostic surveillance, implementing targeted vaccination and eliminating persistently infected animals are essential to reduce BVDV impact in endemic regions such as Argentina.
No takes yet. Share an insight, caveat, or question.
Sosa et al. (2025) conducted an observational in Bovine viral diarrhea virus (BVDV) infection (n=50). BVDV infection was evaluated on Morbidity, mortality, and distribution of lesions. In 50 postnatal BVDV outbreaks in cattle, acute infections and mucosal disease occurred with similar frequency, with no significant differences in morbidity, mortality, or lesion distribution.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: