Key result
General anesthesia with special precautions resulted in an uncomplicated perioperative course with only mild blood pressure fluctuations, compared to severe fluctuations under spinal anesthesia.
Why the study?
Autonomic dysfunction can cause unexpected hemodynamic instability during surgery, and best practices for perioperative care in these patients are not well-defined.
Case Report (n=1)
General anesthesia with special precautions may provide better hemodynamic stability than spinal anesthesia in patients with Charcot-Marie-Tooth disease.
May caution against spinal anesthesia in CMT with autonomic dysfunction; leaves open optimal perioperative strategies.
Autonomic dysfunction can lead to unexpected hemodynamic instability during surgery, and best practices for the perioperative care of patients with this condition are not well-defined. We report the case of a 63-year-old woman with Charcot-Marie-Tooth disease who experienced perioperative autonomic dysfunction characterized by severe fluctuations in blood pressure while under spinal anesthesia. However, <1 month later, a second hip surgery performed under general anesthesia with special precautions resulted in an uncomplicated perioperative course, with only mild fluctuations in blood pressure.
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Maroun et al. (2023) conducted a case report in Charcot-Marie-Tooth disease with perioperative autonomic dysfunction (n=1). General anesthesia with special precautions vs. Spinal anesthesia was evaluated on Perioperative course and blood pressure fluctuations. General anesthesia with special precautions resulted in an uncomplicated perioperative course with only mild blood pressure fluctuations, compared to severe fluctuations under spinal anesthesia.
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