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The Framingham Heart Study identified diabetes as a major cardiovascular risk factor, demonstrating a higher risk of cardiovascular disease in women with diabetes compared to men.
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This review summarizes the historical context and subsequent research stemming from the Framingham Heart Study's identification of diabetes as a major cardiovascular risk factor.
The role of diabetes in the pathogenesis of cardiovascular disease (CVD) was unclear until 1979 when Kannel et al used data from the Framingham Heart Study (FHS) to identify diabetes as a major cardiovascular risk factor. It was also one of the first studies to demonstrate the higher risk of CVD in women with diabetes compared to men with diabetes. Since then, multiple studies have been done to recognize and curtail cardiovascular risk factors such as smoking, obesity, hypertension, hyperlipidemia, and insulin resistance. This review will examine the contribution of the Kannel article and subsequent studies in defining the contribution of several risk factors on cardiovascular disease.
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Qazi et al. (2013) conducted a review in Cardiovascular disease and diabetes. Diabetes and cardiovascular risk factors was evaluated. The Framingham Heart Study identified diabetes as a major cardiovascular risk factor, demonstrating a higher risk of cardiovascular disease in women with diabetes compared to men.
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