Key result
Myasthenic crisis can precipitate Takotsubo cardiomyopathy mimicking an acute myocardial infarction, even in atypically young male patients with a history of thymectomy.
Case Report (n=1)
Takotsubo cardiomyopathy can occur during myasthenic crisis, mimicking acute myocardial infarction, even in atypically young males.
Answers are grounded in this paper and cite their sources.
Reverse Takotsubo may present during respiratory failure with chronic grief; leaves open atypical triggers and variant phenotypes.
Takotsubo Cardiomyopathy is a syndrome characterized by transient and reversible regional myocardial dysfunction in the absence of obstructive coronary artery disease classically resulting in ventricular apical ballooning. It has a strong female predominance with onset generally in seventh decade of life, with hypothesized pathophysiology related to excess of catecholaminergic stimulation, particularly during episodes of physical or emotional stress. Takotsubo cardiomyopathy has been previously reported during myasthenic crisis, the acute deterioration of myasthenia gravis typically involving respiratory failure that is also associated with physical or emotional stress. We present the case of an atypically young male patient with classical takotsubo cardiomyopathy in the setting of myasthenic crisis after thymectomy initially concerning for ST segment elevation myocardial infarction, and a review of the literature of takotsubo cardiomyopathy in myasthenic crisis.
No takes yet. Share an insight, caveat, or question.
Douglas et al. (2018) conducted a case report in Takotsubo Cardiomyopathy and Myasthenic Crisis (n=1). Myasthenic crisis was evaluated. Myasthenic crisis can precipitate Takotsubo cardiomyopathy mimicking an acute myocardial infarction, even in atypically young male patients with a history of thymectomy.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: