Key result
A 61-year-old man with multiple myeloma and profound eosinophilia was diagnosed with nonbacterial thrombotic endocarditis and successfully treated with dexamethasone and aortic valve replacement.
Case Report (n=1)
This case highlights a rare presentation of nonbacterial thrombotic endocarditis causing severe aortic stenosis in a patient with multiple myeloma and profound eosinophilia.
Mini‐Abstract A 61‐year‐old man with no medical history presented with necrosis of the fingers and toes in the setting of newly diagnosed multiple myeloma with profound eosinophilia. A crescendo–decrescendo murmur consistent with aortic stenosis was noted on exam. Transthoracic and transesophageal echocardiography revealed large mass on aortic valve resulting in severe stenosis. Imaging studies and extensive infectious workup were unremarkable for other underlying malignancy, evidence of embolism, infections, or connective tissue disease. Following dexamethasone treatment to achieve a normal eosinophil count, the patient underwent bioprosthetic aortic valve replacement. Pathologic examination was consistent with nonbacterial thrombotic endocarditis.
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Alaiti et al. (2015) conducted a case report in Nonbacterial thrombotic endocarditis (n=1). Dexamethasone and bioprosthetic aortic valve replacement was evaluated. A 61-year-old man with multiple myeloma and profound eosinophilia was diagnosed with nonbacterial thrombotic endocarditis and successfully treated with dexamethasone and aortic valve replacement.
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