Key result
Nonlinear parameters of heart rate variability, except the largest Lyapunov exponent, showed significant statistical differences between normal sinus rhythm, heart failure, and arrhythmias.
Why the study?
Do nonlinear indices of heart rate variability differentiate between normal sinus rhythm, heart failure, and various arrhythmias?
Observational (n=75)
Do nonlinear indices of heart rate variability differentiate between normal sinus rhythm, heart failure, and various arrhythmias?
Nonlinear indices of heart rate variability, excluding the largest Lyapunov exponent, can significantly differentiate between normal sinus rhythm, heart failure, and various arrhythmias.
Nonlinear HRV metrics may aid risk stratification in arrhythmia and HF; leaves open prospective clinical validation.
Heart rate variability (HRV) is the temporal variation between sequences of consecutive heartbeats. Chaos and fractal-based measurements have been widely used for quantifying the HRV for cardiac risk stratification purposes. In this paper, five different sets of HRVs, viz., normal sinus rhythm (NSR), congestive heart failure (CHF), cardiac arrhythmia suppression trial (CAST), supra ventricular tachyarrhythmia (SVTA) and atrial fibrillation (AF), have been analysed using nonlinear parameters to fix the ranges of each parameter. Data were downloaded from the PhysioNet database with 15 sets in each case. The parameters used for analysis were Poincare plot measures: SD1, SD2 and SD12, largest Lyapunov exponent (LLE), correlation dimension (CD); recurrence plot measures: recurrence rate (REC), determinism (DET), mean diagonal length (L mean ), maximal diagonal length (L max ) and entropy (ENTR); detrended fluctuation analysis measures: scaling exponent (α) and fractal dimension (FD); sample entropy (SampEn); and approximate entropy (ApEn). Analysis of variance (ANOVA) was done for confirming the differences in parameter values between various cases. All parameters except LLE showed a significant statistical difference for different cases.
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Asha et al. (2013) conducted an observational in Arrhythmias and Congestive Heart Failure (n=75). Nonlinear parameters of heart rate variability vs. Normal sinus rhythm was evaluated on Differences in nonlinear parameter values between various cardiac conditions. Nonlinear parameters of heart rate variability, except the largest Lyapunov exponent, showed significant statistical differences between normal sinus rhythm, heart failure, and arrhythmias.
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