Key result
Adaptive Postural Balance Cardiac Rehabilitation Exercise significantly reduced HbA1c by 8.87% compared to aerobic exercise alone in patients with coronary artery disease and type 2 diabetes.
Why the study?
The study evaluated the effects of Adaptive Postural Balance Cardiac Rehabilitation Exercise on glycolipid metabolism and exercise endurance in patients with CAD and T2DM, compared with aerobic exercise alone and irregular exercise.
Does Adaptive Postural Balance Cardiac Rehabilitation Exercise (APBCRE) improve glycolipid metabolism and exercise endurance in patients with CAD and T2DM compared to aerobic exercise alone or irregular exercise?
RCT (n=348)
Single-blind
Block randomization with a block size of six
No
Does Adaptive Postural Balance Cardiac Rehabilitation Exercise (APBCRE) improve glycolipid metabolism and exercise endurance in patients with CAD and T2DM compared to aerobic exercise alone or irregular exercise?
Effect estimate: -8.87%
p-value: p=<0.05
Integrating adaptive postural balance training with aerobic exercise provides superior improvements in glycemic control, lipid profiles, and exercise endurance for patients with comorbid CAD and T2DM compared to standard aerobic exercise.
Supports integrating postural balance training into cardiac rehab for CAD-T2DM; extends short-term RCT evidence on exercise modalities but requires outcome trials.
Purpose: This study aimed to evaluate the effects of Adaptive Postural Balance Cardiac Rehabilitation Exercise (APBCRE) on glycolipid metabolism and exercise endurance in patients with coronary artery disease (CAD) and type 2 diabetes mellitus (T2DM). Specifically, we compared the efficacy of APBCRE with aerobic exercise (AE) alone and irregular exercise (IE). Patients and Methods: This randomized controlled trial included 348 patients with CAD, comprising 261 patients with T2DM and 87 non-diabetic CAD patients as a control group. Participants were randomly assigned to one of four groups: the APBCRE group, the AE group, the IE group, or the non-diabetic AE control group. The intervention lasted 8 weeks, including a structured 6-week training phase. Metabolic markers and exercise endurance were assessed at baseline (week 1) and post-intervention (week 8). Cardiopulmonary exercise testing (CPET) was utilized to individualize exercise prescriptions and optimize intervention intensity. Results: The APBCRE group demonstrated significant improvements in fasting blood glucose (FBG) (− 11.34%, from 7.89 to 6.99 mmol/L, p < 0.05), HbA1c (− 8.87%, from 7.20% to 6.56%, p < 0.05), and LDL-C levels (− 12.21%, from 2.44 to 2.14 mmol/L, p < 0.05) compared to the AE and IE groups. While both APBCRE and AE improved lipid profiles, APBCRE demonstrated superior enhancements in exercise endurance, with max increasing by 18.71% (from 14.19 to 16.86 mL/min/kg, p < 0.05) and AT increasing by 16.00% (from 11.62 to 13.48 mL/min/kg, p < 0.05). Conclusion: These findings support the efficacy of APBCRE in improving glycolipid metabolism, exercise endurance, and neuromuscular coordination in patients with CAD and T2DM compared to AE alone.
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Qin et al. (2025) conducted an RCT in Coronary artery disease and type 2 diabetes mellitus (n=348). Adaptive Postural Balance Cardiac Rehabilitation Exercise (APBCRE) vs. Aerobic exercise alone, irregular exercise, and non-diabetic aerobic exercise control was evaluated on Glycated hemoglobin (HbA1c) levels (-8.87%, p=<0.05). Adaptive Postural Balance Cardiac Rehabilitation Exercise significantly reduced HbA1c by 8.87% compared to aerobic exercise alone in patients with coronary artery disease and type 2 diabetes.
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