Key result
Digitalis use in cardiac patients is associated with an increasing incidence of disability due to misuse, highlighting the narrow range between therapeutic and toxic doses.
Why the study?
What are the risks and optimal dosing strategies to prevent digitalis intoxication in cardiac patients?
Population
Cardiac patients, particularly those with advanced and advancing congestive failure
Design
Review
Authors
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Supports cautious digitalis dosing and monitoring; leaves open optimal strategies to minimize toxicity.
What are the risks and optimal dosing strategies to prevent digitalis intoxication in cardiac patients?
The paper highlights the narrow therapeutic index of digitalis and emphasizes the need for careful dosing and monitoring to avoid both toxicity and under-treatment in cardiac patients.
MORTON W. SHRAGER (1957) conducted a review in Digitalis Intoxication. Digitalis was evaluated. Digitalis use in cardiac patients is associated with an increasing incidence of disability due to misuse, highlighting the narrow range between therapeutic and toxic doses.
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