Key result
Admission serum resistin levels were significantly higher in patients with acute STEMI compared to matched controls (13.08 vs 5.31 ng/mL, p < 0.0001).
Case-Control (n=84)
No
Admission serum resistin levels are significantly elevated in patients with acute STEMI compared to healthy controls and inversely correlate with adiponectin levels, suggesting a potential role as an inflammatory biomarker in acute myocardial infarction.
Hypothesis-generating in small Iraqi STEMI cohort; larger prospective studies needed before clinical consideration.
Human resistin is an adipokine, with a possible link to coronary heart disease.A few studies were done about resistin in acute phase of ST-segment elevation myocardial infarction (STEMI) especially in Iraqi patients. Accordingly we design a study to investigate the association between resistin concentration and acute phase of STEMI in Iraqi patients. The present study was carried out at Al-Yarmouk Teaching Hospital from December 2011 until June 2012. Serum resistin levels were measured in 50 patients with acute STEMI (mean age: 58.16 ± 11.73 years) at the first 12 hours of admission and 34 normal controls (mean age: 53.98 ± 15.46 years) matched for age, sex and other risk factors. Resistin level in patients with acute STEMI (13.08 ng/mL) was significantly higher than that of the control group (5.31 ng/mL) (p < 0.0001). The study revealed a significant negative correlation between serum resistin level and serum adiponectin level among patients.
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Kadhim et al. (2017) conducted a case-control in Acute ST-Segment Elevation Myocardial Infarction (STEMI) (n=84). Admission serum resistin level vs. Matched normal controls was evaluated on Admission serum resistin level (ng/mL) (p=<0.0001). Admission serum resistin levels were significantly higher in patients with acute STEMI compared to matched controls (13.08 vs 5.31 ng/mL, p < 0.0001).
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