Alkenyloxy‐substituted aryl bridgeheads have been connected to 2,9‐dichloro‐1,10‐phenanthroline (11) either by Suzuki coupling or by nucleophilic aromatic substitution. The resulting di‐ or tetraalkenes 12 or 17 have been cyclized by ring‐closing metathesis to give concave 1,10‐phenanthrolines 14 and 19, differing from other concave 1,10‐phenanthrolines 1 in their geometries. The influence of the shapes of these ligands and those of the related concave 1,10‐phenanthrolines 1a–f and 2 on the stereochemistry of the copper(I)‐catalyzed cyclopropanation of indene (3) and styrene (4) has been investigated, identifying factors that favour the formation of thermodynamically less stable syn‐cyclopropanes 6 and 7. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)
No takes yet. Share an insight, caveat, or question.
Lüning et al. (2005) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: