Key result
Documented Long COVID is linked to shorter survival length.
Why the study?
Following the implementation of the ICD-10-CM code for Long COVID, this study aimed to evaluate whether documented Long COVID is associated with decreased survival length.
Does documented Long COVID reduce survival length in COVID-positive patients?
Cohort
Yes
Does documented Long COVID reduce survival length in COVID-positive patients?
This study aims to evaluate the impact of Long COVID on survival length using a large US-based electronic health record cohort.
May inform bioengineering models of Long COVID sequelae; leaves open whether interventions alter clinical trajectories.
Since the outbreak of the COVID-19 pandemic in 2020, numerous studies have focused on the long-term effects of COVID infection. On 1 October 2021, the Centers for Disease Control (CDC) implemented a new code in the International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) for reporting 'Post COVID-19 condition, unspecified (U09.9)'. This change indicated that the CDC recognized Long COVID as a real illness with associated chronic conditions. The National COVID Cohort Collaborative (N3C) provides researchers with abundant electronic health record (EHR) data by harmonizing EHR data across more than 80 different clinical organizations in the United States. This paper describes the creation of a COVID-positive N3C cohort balanced by the presence or absence of Long COVID (U09.9) and evaluates whether or not documented Long COVID (U09.9) is associated with decreased survival length.
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Jiang et al. (2025) conducted a cohort in COVID-19. Long COVID (U09.9) vs. Absence of Long COVID was evaluated on Survival length.
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