The shift towards mild and asymptomatic forms of hyperparathyroidism necessitates further research into their long-term prognosis and associated cardiovascular implications.
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Rising mild hyperparathyroidism prevalence warrants no practice change yet; leaves open long-term cardiovascular risks and conservative management for prospective study.
For many years, hyperparathyroidism, including primary, primarily associated with severe pathology of the osseous system and kidneys, was considered a rare disease. The widespread introduction into the clinical practice of the determination in the blood of calcium, and then parathyroid hormone, and osteodensitometry made it possible to recognize this disease more often and at earlier stages and to treat it more successfully. By now, the specific gravity of mild and asymptomatic forms of hyperparathyroidism has increased from 10-15% in the 1980s to 80%. Conservative management of these forms of hyperparathyroidism requires more thorough research on the prognosis of survival, duration and quality of life, and the risk of developing associated diseases in these patients.
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Voronenko et al. (2006) conducted a review in Hyperparathyroidism.
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