In a highly selective reaction the spirocyclotrimer 2 is formed when the phosphaalkyne 1 is treated with the Lewis acid AlCl3. The diphosphet is released when dimethyl sulfoxide (DMSO) is added, and it subsequently rearranges to 1,3,5-triphospha Dewar benzene by cleavage of the PP bond in the diphosphirene unit. This can be trapped with 1 by a homo–Diels–Alder reaction leading to the formation of the tetraphosphacubane 3. All these reaction steps are novel.
No takes yet. Share an insight, caveat, or question.
Breit et al. (1992) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: