Key result
Infective endocarditis in South Africa predominantly affects younger patients with underlying rheumatic heart disease.
Why the study?
Data regarding the epidemiology of infective endocarditis in South Africa, a developing country, is limited.
The epidemiology of infective endocarditis in South Africa differs significantly from developed nations, predominantly affecting younger patients with rheumatic heart disease, yet 1-year mortality remains high at approximately 30%.
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IE now predominantly affects older patients with prosthetic material in developed nations; leaves open optimal prevention strategies for this evolving population.
Pecoraro et al. (2020) conducted a review in Infective endocarditis. Infective endocarditis in South Africa remains predominantly a disease of younger patients with underlying rheumatic heart disease, often caused by penicillin-sensitive Streptococci.
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