Key result
Advanced age, left atrial abnormalities, and prolonged cardiopulmonary bypass predict POAF.
Why the study?
Post-operative atrial fibrillation is a common cardiac surgery complication with adverse outcomes, and identifying predictors is needed to guide prophylaxis, target resources, and clarify underlying pathophysiology.
What are the predictors and biomarkers for post-operative atrial fibrillation after cardiac surgery?
What are the predictors and biomarkers for post-operative atrial fibrillation after cardiac surgery?
Identifying predictors of post-operative atrial fibrillation can help target prophylactic measures to high-risk patients and elucidate the underlying pathophysiology.
Answers are grounded in this paper and cite their sources.
Risk stratification for POAF may optimize prophylaxis after cardiac surgery; leaves open which biomarkers warrant routine clinical use.
Post-operative Atrial fibrillation (POAF) is a common complication post cardiac surgery. It can result in detrimental short- and long-term outcomes due to the increased risk of stroke, cardiac arrest and congestive heart failure in addition to prolonged intensive care and total hospital stay raising the overall healthcare cost. Accurately identifying predictors and biomarkers for POAF ensures that patients at greatest risk can be given the appropriate prophylactic measures; resources can be distributed to the groups who are most in need and where they will gain the optimum effect. Commonly recurring predictors can be investigated further to unveil the pathophysiology behind POAF, which has yet to be fully understood. This literature review aims to examine relevant studies on the proposed predictors of POAF: increased age, gender, history of atrial fibrillation, hypertension, cardiopulmonary bypass time and the use of beta blockers amongst others. This paper will discuss the significance of both the well-known and newfound risk factors to consolidate the areas that require further exploration in order to highlight those at risk and to unravel the mechanism behind POAF.
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Qureshi et al. (2021) conducted a review in Post-operative atrial fibrillation (POAF). Predictors of POAF was evaluated. Various pre-operative, intra-operative, and post-operative factors, including advanced age, left atrial abnormalities, and prolonged cardiopulmonary bypass, are significant predictors of post-operative atrial fibrillation.
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