Key result
Medical management improves acute heart failure and achieves oxygen independence in a single ventricle case.
Why the study?
Single ventricle is increasingly seen in adults following surgical advances, but pharmacological therapies remain ineffective in mitigating the need for heart transplantation when heart failure complications arise.
Case Report (n=1)
No
Highlights the natural evolution and complications, particularly heart failure, in adult survivors of single ventricle physiology, emphasizing the need for better pharmacological management.
Adult single ventricle survival post-childhood surgery supports awareness; leaves open optimal long-term management strategies.
Single ventricle is an uncommon congenital cardiac pathology with high mortality at early ages. However, due to new strategies and timely surgical treatment, it is increasingly seen in adults, which has increased the survival rate. This condition is characterized by a heart with a single functional ventricular cavity. The aim of this article is to report the case of a 40-year-old male with single ventricle, who underwent several surgeries in his childhood. After these surgical procedures, the patient lost medical follow-up and presented complications derived from the disease itself. Heart Failure is a common complication in people with single ventricle, and pharmacological heart failure therapies have been ineffective in mitigating the need of the heart transplantation. That’s why it is essential to develop and apply new pharmacological techniques for the management of these patients in childhood as well as in adulthood. This would allow not only to avoid various comorbidities, but also to improve the quality of life of the patients.
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Carlos et al. (2024) conducted a case report in Single ventricle (double outlet right ventricle and pulmonary stenosis) (n=1). Medical management (Sildenafil, Spironolactone, ASA, Rivaroxaban, Metoprolol) was evaluated on Clinical response to heart failure treatment. Medical management of acute heart failure in a 40-year-old male with single ventricle physiology resulted in clinical improvement and independence from supplemental oxygen.
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