Key result
Review outlines adult Fontan circulation pathophysiology and clinical management, highlighting predictors of HF decompensation.
Why the study?
A growing population of adult patients with a functional single ventricle palliated with the Fontan procedure faces unique pathophysiology, heart failure decompensation, and complications.
This review highlights the unique pathophysiology and clinical management challenges of adult patients with Fontan circulation, focusing on predictors of heart failure decompensation.
Answers are grounded in this paper and cite their sources.
Requires dedicated adult CHD programs in developing countries; leaves open optimal Fontan strategies for resource-limited settings.
The adult population with congenital heart defects of varying complexity is growing rapidly. This includes a significant number of patients over the age of 18 who underwent surgery in early childhood to correct conotruncal anomalies and septal defects. While patients with a functional single ventricle palliated with the Fontan procedure are still relatively rare in developing countries, the expertise gained from managing these patients in expert centers in Europe and the United States of America, as well as the success of pediatric cardiac surgery, has drawn increasing attention to this subject. In this review article, we aim to discuss the unique pathophysiology of Fontan circulation and clinical issues in the management of adult patients, with a particular focus on identifying specific predictors of heart failure decompensation and potential complications in this population.
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Карев et al. (2026) conducted a review in Fontan failure in adult patients. This review outlines the pathophysiology of Fontan circulation and clinical management of adult patients, highlighting specific predictors of heart failure decompensation and potential complications.
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