Background The Fontan operation is the definitive palliation for single-ventricle physiology. In low- and middle-income countries, delayed diagnosis and limited paediatric cardiac services often result in adults presenting for primary Fontan rather than staged completion. Methods Adults (≥18 years) undergoing extracardiac or lateral-tunnel Fontan between January 2021 and June 2025 were retrospectively reviewed. Variables included demographics, conduit and fenestration, cardiopulmonary bypass and cross-clamp times, re-exploration, extubation time, intensive care unit (ICU) stay, pulmonary-artery pressure, atrioventricular valve regurgitation, pleural effusion >14 days, arrhythmia and survival. Results Twenty-four adults (median age 20.5 years (interquartile range 19–22); 17 males (71%)) underwent primary Fontan: 18 (75%) extracardiac and 6 (25%) lateral tunnel. Fenestration was created in 14 (58%). Mean pulmonary-artery pressure increased from 12.6 ± 3.2 to 13.7 ± 3.5 mmHg ( p = .12). Systemic oxygen saturation improved significantly from 79 ± 4% to 92.8 ± 3.1% ( p 14 days occurred in nine (38%) and arrhythmia in three (13%) patients. Kaplan–Meier survival was 100% at 2 years and 95.8% at 3 years (95% confidence interval 83–100). Conclusions Primary Fontan beyond childhood can be performed safely in adults with favourable haemodynamics, achieving excellent early survival and functional improvement. Standardised technique and vigilant postoperative care are central to recovery in low- and middle-income country settings.
Mishra et al. (Tue,) studied this question.