Key result
Review explores physiologic insults triggered by CPB and interventions to neutralize their impact.
This review explores the physiologic insults caused by cardiopulmonary bypass during open-heart surgery and discusses interventions to mitigate these effects.
May guide mitigation of bypass-induced injury in open-heart surgery; leaves open efficacy confirmation in prospective trials.
Despite significant advances made in cardiac surgery over the last 2 decades, the process of bypassing the heart and lungs or cardiopulmonary bypass (CPB) continues to precipitate physiologic insults that have an impact on a patient's ability to recover from open-heart surgery. This article explores some of these potential insults and reviews some of the interventions used to neutralize the impact of CPB.
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Henke et al. (2003) conducted a review in Open-heart surgery and cardiopulmonary bypass. Interventions to neutralize the impact of cardiopulmonary bypass was evaluated. This article reviews the physiologic insults precipitated by cardiopulmonary bypass during open-heart surgery and explores interventions used to neutralize its impact.
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