Key result
Pre-treatment with inhaled bronchodilators and steroids for 10 days before CABG in moderate COPD patients did not significantly reduce 30-day mortality compared to no pre-treatment (1.9% vs 5.9%, p=0.302).
Why the study?
Does a 10-day pre-treatment with inhaled bronchodilators and steroids improve post-operative outcomes in patients with moderate COPD undergoing elective CABG?
Cohort (n=104)
No
Does a 10-day pre-treatment with inhaled bronchodilators and steroids improve post-operative outcomes in patients with moderate COPD undergoing elective CABG?
Absolute Event Rate: 1.88% vs 5.88%
p-value: p=0.302
A 10-day pre-treatment protocol with inhaled bronchodilators and steroids significantly reduces post-operative complications and hospital stay in patients with moderate COPD undergoing elective CABG.
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Does not support routine pre-treatment before CABG in moderate COPD; leaves open need for prospective trials.
Öz et al. (2013) conducted a cohort in Moderate chronic obstructive pulmonary disease (COPD) (n=104). Pre-treatment protocol (inhaled bronchodilator and steroid) vs. No pre-treatment (historical control) was evaluated on 30-day mortality (p=0.302). Pre-treatment with inhaled bronchodilators and steroids for 10 days before CABG in moderate COPD patients did not significantly reduce 30-day mortality compared to no pre-treatment (1.9% vs 5.9%, p=0.302).
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