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The effect of oestrogen on muscle development was determined in 8 muscles (soleus, gastrocnemius, long digital extensor, superficial digital flexor, biceps brachii, brachialis, common digital extensor and triceps brachii) of sexually immature female rabbits. Each rabbit was treated with a physiologic dose of 0.1 ml of stilboestrol dipropionate (synthetic oestrogen) weekly from 3 to 8 weeks of age. The muscle growth, ad determined by increase in muscle weight, was significantly slower in the muscles of oestrogen-treated rabbits as compared with normal rabbits. The degree of the effect of oestrogen varied from one muscle to another.
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E.C. Ihemelandu (1980) studied this question.
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