Key result
Carotid plaques are linked to poor cognitive performance and attention in older men but not women.
Why the study?
Is there an association between carotid atherosclerosis and cognitive impairment in older adults?
Cross-Sectional (n=1,279)
No
Is there an association between carotid atherosclerosis and cognitive impairment in older adults?
Carotid atherosclerosis is moderately associated with poorer cognitive functioning in men aged 59 to 71 years, but not in women.
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Should not yet guide sex-specific cognitive screening; hypothesis-generating for longitudinal carotid-cognition links in men.
Aupérin et al. (1996) conducted a cross-sectional in Cognitive impairment and carotid atherosclerosis (n=1,279). Carotid atherosclerosis (plaques and increased intima-media thickness) vs. Absence of carotid atherosclerosis was evaluated on Poor cognitive performance (lowest quartile on MMSE and neuropsychological tests). The presence of carotid plaques was significantly associated with poor cognitive performance on the MMSE and attention skills in men aged 59 to 71 years, but not in women.
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