Key result
CD36 deficiency affects ~2.2% of healthy blood donors in Shanghai across multiple identified mutations.
Cross-Sectional (n=1,022)
The frequency of CD36 deficiency in the Shanghai population is slightly lower than in other Asian countries, and features several novel genetic mutations.
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May inform CD36-negative platelet donor registries in Shanghai; leaves open clinical transfusion risk estimates pending prospective studies.
Li et al. (2014) conducted a cross-sectional in Healthy blood donors (n=1,022). CD36 deficiency was evaluated on Frequency of Type I and Type II CD36 deficiency. Among 1,022 healthy blood donors in Shanghai, the frequencies of Type I and Type II CD36 deficiency were 0.2% and 2.0%, respectively, with nine different mutations identified.
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