Dual imaging agent: A fluorescent TbIII complex coupled to Fe3O4 nanoparticles and bearing a folic acid residue (see picture) shows superparamagnetism, low cytotoxicity, and high cell uptake, and thus can be used for in vitro fluorescence and magnetic resonance imaging of cells that overexpress the folate receptor, such as HeLa cells.
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Wang et al. (2011) studied this question.
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