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Case Reports1 September 1961Vaccinia GangrenosaReport of a Case and Review of the LiteratureROBERT B. ERICHSON, M.D., M. J. MCNAMARA, M.D.ROBERT B. ERICHSON, M.D., M. J. MCNAMARA, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-55-3-491 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptVaccinia gangrenosa is a rare complication of smallpox vaccination characterized by progressive spread and necrosis of the primary inoculation site, metastatic vaccinial lesions, sometimes occurring in multiple outcroppings, and a uniformly fatal outcome when not specifically treated. Of the several important complications of smallpox vaccination, it is the least common and has the poorest prognosis. The following case is the twelfth to be reported fully in the literature in English, the third involving an adult, and the third in which the disease itself was not fatal.CASE REPORTA 58-year-old white man was admitted to The New York Hospital on...References1. ACLANDFISHER TDCH: A case of generalized vaccinia. Trans. Clin. Soc. Lond. 26: 114, 1893. Cited by Keiden et al. (7). Google Scholar2. SHORTT CJ: A case of generalized vaccinia. Brit. Med. J. 1: 1004, 1933. Google Scholar3. CONYBEARE ET: Reports of the Chief Medical Officer of Health, Part II, p. 26, 1949-50. Cited by Laurance et al. (6). Google Scholar4. CROSBIEDOWNIE WA: Personal communication. Cited by Keiden et al. (7). Google Scholar5. BIGLERSLOTKOWSKI JE: Smallpox vaccination with prolonged vaccinia. Pediatrics 7: 24, 1951. MedlineGoogle Scholar6. LAURANCECUNLIFFEDUDGEON BACJA: Vaccinia gangrenosa—the report of a case of prolonged generalized vaccinia. Arch. Dis. Child. 27: 482, 1952. CrossrefMedlineGoogle Scholar7. 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CrossrefMedlineGoogle Scholar19. MARSHALLWHITE AR: Reactions of the reticular tissues to antigens. Brit. J. Exp. Path. 31: 157, 1950. MedlineGoogle Scholar20. DIBLEGLEAVES JH: Histological and experimental observations on generalized vaccinia in man. J. Path. Bact. 38: 29, 1934. CrossrefGoogle Scholar21. HALLCUNLIFFEDUDGEON GFACJA: Prolonged generalized vaccinia. J. Path. Bact. 66: 25, 1953. CrossrefMedlineGoogle Scholar22. LARSONTOMLINSON DLLJ: Quantitative antibody studies in man. III. Antibody response in leukemia and other malignant lymphomata. J. Clin. Invest. 32: 317, 1953. CrossrefMedlineGoogle Scholar23. APT L, in Yearbook of Pediatrics, Year Book Publishers, Inc., Chicago, Ill., 1953, p. 67. Google Scholar24. KEMPEBENENSON CAS: Smallpox and vaccinia, in Symposium on Unusual Infections of Childhood: Laboratory Tests and Specialized Procedures. Pediat. Clin. N. Amer., Feb. 1955, pp. 30-31. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.Received for publication June 27, 1960.From the Department of Medicine and the Section on Virus Research of the Department of Public Health, New York Hospital, New York, N. Y.Dr. McNamara is a Fellow of the National Foundation.Requests for reprints should be addressed to Robert B. Erichson, M.D., Syracuse Medical Center, Syracuse, N. Y. 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KARZON, M.D., ALMEN L. BARRON, PH.D., MARTIN E. PLAUT, M.D., VILAYAT M. ALI, M.D.Vaccinia GangrenosaEXFOLIATIVE GASTRIC CYTOLOGYSEROTHERAPY IN VIRUS DISEASES 1 September 1961Volume 55, Issue 3Page: 491-498KeywordsHospital medicineInoculationLesionsNecrosisPathogenesisPrevention, policy, and public healthSmallpox Issue Published: 1 September 1961 PDF DownloadLoading ...
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