Key result
Severe preoperative right ventricular dysfunction significantly increased postoperative mortality to 30.0% compared to 0.0% in patients with normal right ventricular function.
Why the study?
To investigate the impact of preoperative RV function on postoperative outcomes, including mortality and reoperation rates, in patients undergoing tricuspid valve surgery.
Does preoperative right ventricular dysfunction increase postoperative mortality and reoperation rates in patients undergoing tricuspid valve surgery?
Cohort (n=100)
No
Does preoperative right ventricular dysfunction increase postoperative mortality and reoperation rates in patients undergoing tricuspid valve surgery?
Absolute Event Rate: 30% vs 0%
p-value: p=0.035
Preoperative right ventricular dysfunction, particularly when severe, significantly increases the risk of 30-day mortality and reoperation in patients undergoing tricuspid valve replacement.
Severe preoperative right ventricular dysfunction may indicate higher postoperative mortality; hypothesis-generating and requires prospective confirmation.
Objective: This study aimed to investigate the impact of preoperative right ventricular (RV) function on postoperative outcomes such as mortality, reoperation rates, valve size, and other clinical variables in patients undergoing tricuspid valve surgery. Methods: This retrospective study included 100 patients who underwent tricuspid valve surgery. Patients were categorized into four groups based on preoperative RV function: normal, mildly depressed, moderately depressed, and severely depressed. RV function was assessed using echocardiographic parameters, including tricuspid annular plane systolic excursion (TAPSE), tissue Doppler imaging (TDI), mean pulmonary artery pressure (MPAB), and valve size. Postoperative outcomes, including mortality and reoperation rates, were analyzed. Results: Patients with severely depressed RV function had significantly higher mortality rates (p=0.035). Reoperation rates also increased as RV function worsened (p=0.006). No significant difference was found between groups regarding valve size (p>0.05) or the type of surgery (sternotomy or thoracotomy) (p=0.714). Conclusion: Right ventricular dysfunction significantly increases postoperative mortality and reoperation rates in patients undergoing tricuspid valve surgery. Careful preoperative evaluation of RV function, including valve size, is critical for improving surgical outcomes.
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Sağlam et al. (2024) conducted a cohort in Tricuspid valve surgery (n=100). Preoperative right ventricular dysfunction vs. Normal right ventricular function was evaluated on Postoperative mortality (p=0.035). Severe preoperative right ventricular dysfunction significantly increased postoperative mortality to 30.0% compared to 0.0% in patients with normal right ventricular function.
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